Controllable Jet Injection of Dental Local Anaesthetic

Objective: Fear of dental procedures is a common barrier to effective care. A promising technique overcome anxiety needle-free jet injection, which involves delivering local anaesthetic as high-speed capable penetrating the oral mucosa without needle. Previous efforts have used loud, uncontrolled injectors designed for transdermal delivery that failed achieve significant uptake in practice. Methods: In this work, we present and validate controllable injection device driven by silent electric motor anaesthetic. The injector includes novel tubular attachment at its distal end, allows be performed comfortably throughout mouth. expected pressure loss resulting from use analysed. This analysis predicted 75 mm long 0.53 radius would result negligible loss. To human tissue, system was perform 18 injections into mouths two Thiel-embalmed cadavers. These were visualised using cone-beam computed tomography (CBCT). Results: Benchtop testing prototype verified along attachment. CBCT scans demonstrated fluid successfully delivered desired locations, adjacent root apex teeth, every site. Conclusion: outcomes performance injector, demonstrating potential tool reduce anxiety. Clinical Translational Impact Statement- Our overcomes key limitations associated with previous attempts deliver needle-free. could greatly barriers